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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1798

Title: Prevalence of Helicobacter Pylori Infection among HIV-1 Infected Patients using Stool Antigen Tests in Jos, North-Central, Nigeria
Authors: Onyemocho, Audu
Ajala, Adaiche Rosemary
Ocheme, Okojokwu Julius
Murna, Ali
Amali, Adekwu
Lar, Patricia
Ifeanyi, Smith Stella
Keywords: Enzyme immunoassay
Issue Date: 2016
Publisher: Govaresh
Citation: Anejo-Okopi AJ, Audu O, Adaiche AR,Okojokwu OJ, Ali M, Adekwu A, Lar P, Smith SI. Prevalence of Helicobacter Pylori Infection among HIV-1 Infected patients using Stool Antigen Tests in Jos, North-Central, Nigeria. Govaresh 2016:21:55-63.
Series/Report no.: Vol. 21;No.1; Pp 55-63
Abstract: Background: Helicobacter pylori (H. pylori) infection is common among humans and plays a major role in the etiology of peptic ulcer disease with significant morbidity in patients with HIV-1 on antiretroviral therapy. There are conflicting prevalence patterns of H. pylori in HIV-1 infected patients using various methods of detection. The noninvasive technique used for detection of H. pylori infection is inexpensive and convenient with no complications. Materials and Methods: We aimed to determine the prevalence of H. pylori infection among patients infected with HIV-1 on antiretroviral therapy using H. pylori stool antigen. 139 patients infected with HIV-1 were recruited, stool samples were collected and the H. pylori stool antigen (HpSA) test was used to detect H. pylori antigen. Results: 46.8% of the respondents were positive for H. pylori and 53.2% were negative, 18 (13%) were men and 47 (33.8%) were women. HpSA is a relatively simple, inexpensive, and time-saving non-invasive test for the detection of H. pylori infections in patients infected with HIV-1. Conclusion: We also observed that the prevalence of H. pylori was low in these patients compared with the general population. However, more studies using H. pylori stool antigen test are needed in these patients in the North-Central, Nigeria to further evaluate the infection rate.
URI: http://hdl.handle.net/123456789/1798
Appears in Collections:Microbiology

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