An HIV-1 Infected Patient with Neurofibromatosis Type 1: A Case Report.

Abstract

Background: Although HIV-1 infection predisposes an individual to well defined neoplasia, neurofibromas have not been reported as some of the typical ones. The association between HIV-1 infection and neurofibromatosis type 1, a genetic disorder, should be of interest because HIV infection could alter the natural biology of its cutaneous manifestations. However, reports on simultaneous occurrence of these conditions in an individual are rare. Method: The case records of a 30 year old HIV 1 positive female receiving care at the Jos University teaching hospital centre and a review of the relevant literature was utilised. Result: We present a 30 year old HIV positive woman with florid cutaneous lesions of familial neurofibromatosis type 1 who had adequate response to antiretroviral therapy Conclusion: HIV infection and treatment did not seem to affect the clinico- pathological features of the neurofibromatosis lesions