DSpace
 

University of Jos Institutional Repository >
Health Sciences >
Biochemistry >

Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1203

Title: Potentials of Methanolic Extract of N. Latifolia Stem Bark Against T. Congolense Infection in Experimental Rats
Authors: Longdet, I. Y.
Achemu, H.U.
Okanlawon, C.N.
Keywords: Trypanosoma congolense
Trypanosomiasis
Nauclea latifolia
Issue Date: 2014
Publisher: Journal of Agricultural Sciences and Policy Research
Series/Report no.: Volume 4, Number 2;PP. 28-41
Abstract: Methanolic extract of Nauclea latifolia stem bark was investigated for antitrypanosomal activity using albino rats infected with Trypanosoma congolense. Fifteen albino rats placed in 5 groups of 3 each were labeled A to E. Groups A and B served as positive and negative controls, respectively. Groups C, D and E were infected with the parasites and treated with 100, 200 and 300mg/kg body weight of methanolic extract of Nauclea latifolia stem bark respectively. Parasitemia was monitored as well as hematological and biochemical parameters were analyzed. The results showed suppression in levels of parasites in all the infected and treated groups. Equally, the negative effects of the disease were lowered as shown in the hematological and biochemical parameters. The antitrypamosomal potential of the extracts was therefore demonstrated.
URI: http://hdl.handle.net/123456789/1203
Appears in Collections:Biochemistry

Files in This Item:

File Description SizeFormat
Page 28-41 _233_.pdf165.93 kBAdobe PDFView/Open
View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback