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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1227

Title: The Effect of Ricinus Communis-Linn (Ricom 1013-J) on Semen Parameters: A Comparative Study
Authors: Ekwere, Ekwere Okon
McNeil, Rosaleen Thecla
Okwuasaba, Francis Kanayo
Keywords: Castor plant
Diane35
Semen analysis
Issue Date: 2011
Publisher: Journal of Physics: Conference Series (JPCS)
Series/Report no.: Vol. 1;Pp 7-11
Abstract: Objectives: The seed variety of Ricinus communis-linn (RICOM 1013-J) is a popular contraceptive agent among the Rukuba women of Central Nigeria. The aim of this study is to compare the effect of RICOM 1013-J to that of an anti-androgen, diane-35 (which contains 0.035g cyproterone acetate and 2mg of ethinyl oestradiol), on testicular histology and function. Material and Methods: Adult male Wistar rats weighing 200-250g were used for this experiment. The animals were administered orally with 0.41mg/kg of diane-35, RICOM 1013-J (10mg/kg) and10mg/kg of normal physiological saline, for the control group. The rats were then weighed weekly for six weeks. Results and Conclusions: The semen parameters measured showed marked suppression of testicular function in the groups treated with RICOM 1013-J and diane-35, when compared to that of the control. It can therefore be concluded that RICOM 1013-J suppresses testicular histology and function and is a potential male contraceptive agent.
URI: http://hdl.handle.net/123456789/1227
Appears in Collections:Anatomy

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