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|Title: ||Lactobacillus Casei Isolates from Kunun Zaki: The Probiotic Potential Against Induced Shigellosis in Experimental Rats|
|Authors: ||Kutshik, Richard J.|
Longdet, Ishaya Y.
Atuluku, Victor A.
|Keywords: ||Shigella dysenteriae|
|Issue Date: ||Jun-2012|
|Publisher: ||Journal of Medical and Applied Biosciences|
|Series/Report no.: ||Vol. 4;Pp 46-53|
|Abstract: ||Two different volumes of Lactobacillus casei isolates (0.4ml of 2.0 x 1010 CFU/ml and 0.4ml of 4.0 x 1010 CFU/ml) from a local beverage (kunun zaki) cultured on MRS agar were orally administered to different groups of shigella–free experimental rats. Both groups were
subsequently dosed with 0.4ml 1.0x105CFU/ml of Shigella dysenteriae and studied along with set control groups. The results from the rectal temperature, feed consumed, weight gained and biochemical tests revealed that L. casei isolates from kunun zaki exhibited impressive potential against bacillary dysentery. The probiotic efficacy of the L. casei isolates tends to be dose dependent.|
|Appears in Collections:||Biochemistry|
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