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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1233

Title: Lactobacillus Casei Isolates from Kunun Zaki: The Probiotic Potential Against Induced Shigellosis in Experimental Rats
Authors: Kutshik, Richard J.
Longdet, Ishaya Y.
Egbere, O.J.
Atuluku, Victor A.
Keywords: Shigella dysenteriae
Issue Date: Jun-2012
Publisher: Journal of Medical and Applied Biosciences
Series/Report no.: Vol. 4;Pp 46-53
Abstract: Two different volumes of Lactobacillus casei isolates (0.4ml of 2.0 x 1010 CFU/ml and 0.4ml of 4.0 x 1010 CFU/ml) from a local beverage (kunun zaki) cultured on MRS agar were orally administered to different groups of shigella–free experimental rats. Both groups were subsequently dosed with 0.4ml 1.0x105CFU/ml of Shigella dysenteriae and studied along with set control groups. The results from the rectal temperature, feed consumed, weight gained and biochemical tests revealed that L. casei isolates from kunun zaki exhibited impressive potential against bacillary dysentery. The probiotic efficacy of the L. casei isolates tends to be dose dependent.
URI: http://hdl.handle.net/123456789/1233
ISSN: 2277-0054
Appears in Collections:Biochemistry

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