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|Title: ||Treatment Outcome of Human Immunodeficiency Virus Infected Children: A Retrospective Cohort Study in a Private Hospital in Nigeria|
|Authors: ||Ochoga, Martha Omoo|
Ejeliogu, Emeka U.
Abah, Rose O.
Ebonyi, Augustine O.
|Issue Date: ||2015|
|Publisher: ||Open Science Journal of Clinical Medicine|
|Citation: ||Martha Omoo Ochoga, Onyemocho Audu, Emeka U. Ejeliogu, Ame Idoko, Rose O. Abah, Augustine O. Ebonyi. Treatment Outcome of Human Immunodeficiency Virus Infected Children: A Retrospective Cohort Study in a Private Hospital in Nigeria. Open Science Journal of Clinical Medicine. Vol. 3, No. 4, 2015, pp. 136-139.|
|Series/Report no.: ||Vol. 3;No. 4; Pp 136-139|
|Abstract: ||Background: The pandemic of Human Immunodeficiency Virus (HIV) and Acquired immunodeficiency syndrome (AIDS) has
reversed many of the health and developmental gains over the past three decades, especially in low income countries. This
study assessed the treatment outcome of HIV-infected children after two years on highly active antiretroviral therapy (HAART)
in a private health facility in Benue State, North-Central Nigeria. Methodology: A retrospective study was employed to review
the clinical records of HIV-infected children from January 2004 to December 2014. Data obtained was analysed with Statistical
packages for social sciences (SPSS) version 20.0. Chi-square (χ2) test was used for test of association between the independent
variables and the main outcomes of the study, with P value set at 0.05. Results: One hundred and one children were initiated on
HAART within the period. The mean age of the patients was 8.5±3.0 years. Majority (43.6%) of those initiated on HAART had
World Health Organization (WHO) clinical stage 2 disease while 63.4% were on cotrimoxazole prophylaxis. Ten (9.9%) were
lost to follow up, 4.0% were transferred to a tertiary health facility while 2.0% died. Overall patients with baseline CD4 count
of >350 cell/mm3 and those with WHO stages 1 and 2 disease had higher rates of survival after two years on HAART.
Conclusion: With prompt access to Antiretroviral Therapy (ART0 majority of HIV-1 infected children diagnosed early can now
|Appears in Collections:||Paediatrics|
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