Tamsulosin 0.4mg in the Treatment of Symptomatic BPH: Assessment of Response in African Men

Abstract

Introduction: To assess the presence and extent of response to Tamsulosin 0.4mg in African men with lower urinary tract symptoms (LUTS) due to Benign Prostatic Hyperplasia (BPH) over a short term. Materials and Methods : A total of 106 men were enrolled in the study. After assessing the severity of their LUTS using the International Prostate Symptom Score (IPSS) and the Quality Of Life (QOL) Score, patients were assigned to 0.4mg Tamsulosin (ContifloR). At 4 weeks the IPSS and QOL were re-assessed. Results : Two patients (1.9%) were lost to follow up along the course of the study. Mean age of patients was 63.9years age while range was 41-90 years. Mean IPSS at baseline was 18.04, whereas mean QOL score was 5.15. There was statistically significant improvement in IPSS and QOL Score from baseline at 4 weeks. The pooled mean IPSS showed a 47.7 % (p<0.001) improvement while the QOL score showed a 38.9% (p=0.00) improvement at the end of the study. Conclusion: Our study demonstrated that African men with LUTS due to BPH can expect significant improvement in their symptoms while using Tamsulosin 0.4 mg.