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|Title: ||Late Commencement of Anti-Tuberculosis Drugs in Three Directly Observed Treatment Short Course Centres in Benue State Nigeria: A Neglected Correlate of Tuberculosis Management|
|Authors: ||Audu, Onyemocho|
Joshua, Istifanus A.
Anefu, Gabriel O.
Isa, Samson Ejiji
|Issue Date: ||28-Jan-2017|
|Publisher: ||Journal of Tuberculosis Research|
|Citation: ||Audu, O., AgelaIgbabul, S., Anejo-Okopi, J., Joshua, I.A., Anefu, G.O. and Isa, S.E. (2017) Late Commencement of Anti-Tuberculosis Drugs in Three Directly Observed Treatment Short Course Centres in Benue State Nigeria: A Neglected Correlate of Tuberculosis Management. Journal of Tuberculosis Research, 5, 95-105.|
|Series/Report no.: ||Vol. 5;Pp 96-105|
|Abstract: ||Background: Most researches on the correlate of Tuberculosis (TB) treatment
outcomes place emphasis on sociodemographic characteristics of the patients,
Human Immunodeficiency Virus status and CD4⁺ count of patients and nutrition
among others. This study assessed the effect of delay in commencement
of anti-TB regimen on the treatment outcomes of all Tuberculosis patients
treated between 2011 and 2014 in three directly observed treatment
short course centres in Benue State, Nigeria. Methodology: A retrospective
cohort study with convenient sampling technique was used for all registered
Tuberculosis patients enrolled for treatment within the reviewed period. Chisquare
(χ2) test was used for test of association between the independent variables
and the main outcomes of the study, with statistical significance set at
p-value of 5%. Results: Of the total 1711 cases reviewed, the males to females
ratio was 3.9:1. The mean age for the males’ patients was 39.0 ± 15.3 years and
the females 33.7 ± 14.2 years. Majority of the patients were new pulmonary
Tuberculosis cases and they commenced their treatment after 3 weeks of diagnosis.
Higher failure and death rate were reported amongst the patients who
commenced their treatment late (78.7% and 42.5% respectively). The relationship
between the treatment outcome and the time of commencement of
anti-TB drug regimen was statistically significant (p < 0.005).|
|Appears in Collections:||Microbiology|
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