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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/3017

Title: Methylated Spirit Versus 4% Chlorhexidine Gel in Neonatal Umbilical Cord Infection: A Short Report of a Randomized, Openlabelled, Parallel-Group Trial
Authors: Shwe, D.D.
Abok, I.I.
Diala, U.M.
Egbodo, C.
Toma, B.O.
Nathan, S.
Pam, V.C.
Ocheke, A.
Oguche, S.
Keywords: mortality
Cord separation time
Neonatal sepsis
Issue Date: 2018
Publisher: Nigerian Journal of Paediatrics
Series/Report no.: Vol. 45;No. 2; Pp 1-4
Abstract: Background: Neonatal sepsis is a known leading cause of neonatal morbidity and mortality. Aim: To compare the efficacies of 96% methylated spirit and 4% chlorhexidine (CHX) gel in the treatment of umbilical stump of neonates. Method: This was a randomized, open labelled, parallel group trial of CHX gel and Methylated spirit for neonatal umbilical cord care in Jos, between 2/6/17 and 16/7/17. Inclusion criteria were term, newly born 0 to 6 hours old, with no known risk for sepsis and written informed parental consent. Eligible subjects were randomized to receive methylated spirit or 4% CHX gel. Outcome measures were cord separation time, omphalitis, neonatal sepsis and neonatal mortality by day 28. Results: A total sample of 51 of 58 met enrolment criteria. Thirtytwo (62.7%) where delivered in JUTH, 33(64.7%) were males with a mean birth weight of 3.7kg (CI 3.04 – 3.30). Mean cord separation times were 7.96 ± 4.07)days in the methylated spirit group vs 6.43 ± 3.13days in the CHX comparator group, (p=0.078). Omphalitis was0% vs2(8.3%) and NNS 2 (7.4%)vs2(8.3%) in methylated spirit and CHX treatment groups respectively. There was 1(3.7%) mortality in the methylated spirit treatment group. Conclusion: Methylated spirit and 4% CHX gel have comparable umbilical stump treatment efficacy. Methylated spirit may be a safe alternative in clinical settings where topical 4% CHX gel is unavailable or unsafe.
URI: http://hdl.handle.net/123456789/3017
Appears in Collections:Paediatrics

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