University of Jos Institutional Repository >
Medical Sciences >
Please use this identifier to cite or link to this item:
|Title: ||Methylated Spirit Versus 4% Chlorhexidine Gel in Neonatal Umbilical Cord Infection: A Short Report of a Randomized, Openlabelled, Parallel-Group Trial|
|Authors: ||Shwe, D.D.|
Cord separation time
|Issue Date: ||2018|
|Publisher: ||Nigerian Journal of Paediatrics|
|Series/Report no.: ||Vol. 45;No. 2; Pp 1-4|
|Abstract: ||Background: Neonatal sepsis is a known leading cause of neonatal morbidity and mortality.
Aim: To compare the efficacies of 96% methylated spirit and 4% chlorhexidine (CHX) gel in the treatment of umbilical stump of
Method: This was a randomized, open labelled, parallel group trial of CHX gel and Methylated spirit for neonatal umbilical cord care in Jos, between 2/6/17 and 16/7/17.
Inclusion criteria were term, newly born 0 to 6 hours old, with no known risk for sepsis and written informed parental consent.
Eligible subjects were randomized to receive methylated spirit or 4% CHX gel. Outcome measures were cord separation time, omphalitis, neonatal sepsis and neonatal
mortality by day 28.
Results: A total sample of 51 of 58 met enrolment criteria. Thirtytwo (62.7%) where delivered in JUTH, 33(64.7%) were males with
a mean birth weight of 3.7kg (CI 3.04 – 3.30). Mean cord separation times were 7.96 ± 4.07)days in the methylated spirit group vs 6.43 ± 3.13days in the CHX comparator
group, (p=0.078). Omphalitis was0% vs2(8.3%) and NNS 2 (7.4%)vs2(8.3%) in methylated
spirit and CHX treatment groups respectively. There was 1(3.7%) mortality in the methylated spirit treatment group.
Conclusion: Methylated spirit and 4% CHX gel have comparable umbilical stump treatment efficacy. Methylated spirit may be a
safe alternative in clinical settings
where topical 4% CHX gel is unavailable
|Appears in Collections:||Paediatrics|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.