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|Title: ||Effects of Aqueous Extract of Ipomoea batatas Leaf on Blood Glucose, Kidney Functions and Hematological Parameters of Streptozotocin-Induced Diabetic Rats|
|Authors: ||Rafiu, AA|
Luka, C. D.
High blood sugar
|Issue Date: ||2018|
|Publisher: ||Journal of Research in Diabetes & Metabolism|
|Citation: ||Rafi u AA, Luka CD. Effects of Aqueous Extract of Ipomoea batatas Leaf on Blood Glucose, Kidney Functions And Hematological Parameters Of Streptozotocin-Induced Diabetic Rats. J Res Diabetes Metab. 2018;4(1): 004-009.|
|Series/Report no.: ||Vol.4;Iss.1: Pp.004-009|
|Abstract: ||Diabetes mellitus as reported by is a complex disorder that affects metabolism in humans and other subjects, affecting several
organs in the system. Management of diabetes is challenging and its treatments are often associated with side effects as scientist is
increasingly demanding for natural products with antidiabetic activity and fewer side effects [1,2]. In this study, the effect of aqueous
Ipomoea batatas leaf extract was carried out in streptozotocin- induced diabetic rats (55 mg/ kg) body wt. for 28days. The continuous
administration of extract from 400 mg/ kg body wt. for 28days signifi cantly (P ˂ 0.05) reversed the effects on blood glucose which was
initially increased. There was a signifi cant decrease (P ˂ 0.05) in urea, creatinine, and uric which show kidney impairment following
induction of the diabetogen. There was signifi cant increase (P ˂ 0.05) in the PCV, Hb, RBC, Neutrophils, Basophils, and Monocytes.
While Wbc, platelets, lymphocytes, and Eosinophils were signifi cantly (P ˂ 0.05) decreased. The study therefore reveals that aqueous
Ipomoea batatas leaf extract can be used in hyperglycemia management as well as in improvement in kidney and blood hematological
|Appears in Collections:||Biochemistry|
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