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Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/861
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| Title: | Analysis of Some Biochemical and Haematological Parameters for Mucuna Pruriens (DC) Seed Power in Male Rats |
| Authors: | Ndukwe, Henry Chukwudi
Omale, Simeon
Aguiyi, John Chinyere |
| Keywords: | alanine aminotransferase
aspartate aminotransferase |
| Issue Date: | Oct-2011 |
| Publisher: | Pakistan Journal of Pharmaceutical Sciences |
| Series/Report no.: | Vol. 24;No. 4; Pp 523-526 |
| Abstract: | The biochemical and haematological effects of the seed powder of Mucuna pruriens in male rats were evaluated
to establish some biological properties of this potential biopesticide currently undergoing investigation. The
result showed that Mucuna pruriens seed extract produced a significant (P<0.05) increase in white blood cell
(WBC) count, as well as in bilirubin concentrations, alkaline phosphatase (ALP), protein and creatinine levels
measured. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were significantly reduced
(P<0.05) in comparison with the experimental control. PCV, Hb, albumin level and WBC differential counts
gave no significant difference between treated and control groups. The results revealed metabolic imbalance in
the rats which suggests a mild cholestasis effect of the extract. |
| URI: | http://hdl.handle.net/123456789/861 |
| Appears in Collections: | Clinical Pharmacy and Pharmacy Practice
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